产品货号：
Z31991
中文名称：
EGFR抗体
英文名称：
Anti-EGFR Antibody (Clone#OTI2G8)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-EGFR Antibody (Clone#OTI2G8) |
| 指标别名 | EGFR;EGFR-Specific;ERBB;ERBB1;HER1;mENA;PIG61;Proto oncogene c ErbB 1 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IF |
| 基因名称 | EGFR |
| 克隆号 | OTI2G8 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG1 |
| 免疫原 | Full length human recombinant protein of human EGFR(NP_958440) produced in HEK293T cell. |
| 实际分子量 | 42.4KD |
| 成分 | PBS (PH 7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. |
| 纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Stable for 12 months from date of receipt.Store at -20℃ as received. |
| 背景资料 | The epidermal growth factor receptor (EGFR;ErbB-1;HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands.It is a member of the ErbB family of receptors,a subfamily of four closely related receptor tyrosine kinases:EGFR (ErbB-1),HER2/c-neu (ErbB-2),Her 3 (ErbB-3) and Her 4 (ErbB-4).EGFR exists on the cell surface and is activated by binding of its specific ligands,including epidermal growth factor and transforming growth factor alpha (TGFalpha).EGFR and its ligands are cell signaling molecules involved in diverse cellular functions,including cell proliferation,differentiation,motility,and survival,and in tissue development.Mutations that lead to EGFR overexpression (known as upregulation) or overactivity have been associated with a number of cancers,including lung cancer and glioblastoma multiforme.In this latter case a more or less specific mutation of EGFR,called EGFRvIII is often observed. |
| Uniprot ID | P00533 |
| 基因名全称 | epidermal growth factor receptor |
| 蛋白名全称 | Epidermal growth factor receptor |
| 推荐稀释比 | Western blot (WB) 1:4000 Immunofluorescence (IF) 1:100 |
相关搜索：EGFR抗体，EGFR单抗，Anti-EGFR Antibody (Clone#OTI2G8)